Aurora A, Meiosis and Mitosis
نویسندگان
چکیده
منابع مشابه
Mitosis and Meiosis
Introduction As we discussed in class, biological growth is a multi-dimensional phenomena. In essence, the basic unit of life, the cell, must duplicate itself. One "mother" cell must become two "daughter" cells, through the process of Cell Division, mostly MITOSIS. This is a completely asexual event and involves replication of the nucleus and its constituents and dividing up of the cytoplasm, t...
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Condensin complexes are essential for mitotic and meiotic chromosome segregation. Caenorhabditis elegans, like other metazoans, has two distinct mitotic and meiotic condensin complexes (I and II), which occupy distinct chromosomal domains and perform non-redundant functions. Despite the differences in mitotic and meiotic chromosome behavior, we uncovered several conserved aspects of condensin t...
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Apomixis, or asexual clonal reproduction through seeds, is of immense interest due to its potential application in agriculture. One key element of apomixis is apomeiosis, a deregulation of meiosis that results in a mitotic-like division. We isolated and characterised a novel gene that is directly involved in controlling entry into the second meiotic division. By combining a mutation in this gen...
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Attachment of sister chromatids to microtubules from opposite spindle poles--bi-orientation--generates tension at the kinetochores. The Ipl1/Aurora B kinase responds to the absence of tension at mono-oriented chromosomes and promotes microtubule turnover and spindle checkpoint activation until a stable bi-oriented attachment is achieved.
متن کاملAurora-A regulates MCRS1 function during mitosis
The mitotic spindle is made of microtubules (MTs) nucleated through different pathways involving the centrosomes, the chromosomes or the walls of pre-existing MTs. MCRS1 is a RanGTP target that specifically associates with the chromosome-driven MTs protecting them from MT depolymerases. MCRS1 is also needed for the control of kinetochore fiber (K-fiber) MT minus-ends dynamics in metaphase. Here...
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ژورنال
عنوان ژورنال: Biology of the Cell
سال: 2004
ISSN: 0248-4900
DOI: 10.1016/j.biolcel.2003.09.008