Auer Rods Galore!

Auer rods in unusual sites: macrophage indigestion

Auer Rods Are Not Seen in Non-Neoplastic Cells

First I would like to thank Smeeta Gajendra for scrutinizing my article in her ‘Comment: In Response to “Auer Rod-Like Inclusions in Reactive Plasma Cells in a Case of Acute Myeloid Leukemia”’ published online and for bringing to light the missing reference of Sharma et al. [1], who reported a case of Auer rodlike inclusions in plasma cells in a case of therapy-related AML. I sincerely regret m...

Crystal structure of Auer rods in acute myeloblastic leukaemia (AMyL).

Ultrathin sections containing Auer rods from cases of acute myeloblastic leukaemia (AMyL) were tilted in the goniometer stage of the electron microscope and the resulting series of electronmicrographs analysed in an optical diffractometer illuminated by laser. The results showed that Auer rods of AMyL show a truly three dimensional crystal structure. Measurements from the optical diffraction pa...

Auer Rods in Chronic Myelomonocytic Leukemia Can Change the Diagnosis

Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping morphological features of myelodysplastic and myeloproliferative disease and a potential risk of transformation to acute myeloid leukemia. Presence of Auer rods in CMML is a rare finding and the presence of an occasional Auer rod gives the diagnosis of CMML-2 in spite of the presence of <5% blas...

Low blast count myeloid disorders with Auer rods: a clinicopathologic analysis of 9 cases.

Auer rods are a hallmark of acute myeloid leukemia but occasionally are seen in myelodysplastic syndromes (MDSs) or chronic myelomonocytic leukemia, rarely in cases with fewer than 5% blasts. The significance of this finding is unclear. We report 9 cases of this unusual phenomenon. All patients had cytopenias, isolated to a single lineage in 4. Circulating blasts were present in 8 cases (rare t...