Auditory processing during deep propofol sedation and recovery from unconsciousness
نویسندگان
چکیده
منابع مشابه
Auditory processing during deep propofol sedation and recovery from unconsciousness.
OBJECTIVE Using evoked potentials, this study investigated effects of deep propofol sedation, and effects of recovery from unconsciousness, on the processing of auditory information with stimuli suited to elicit a physical MMN, and a (music-syntactic) ERAN. METHODS Levels of sedation were assessed using the Bispectral Index (BIS) and the Modified Observer's Assessment of Alertness and Sedatio...
متن کاملThalamus, Brainstem and Salience Network Connectivity Changes During Propofol-Induced Sedation and Unconsciousness
In this functional magnetic resonance imaging study, we examined the effect of mild propofol sedation and propofol-induced unconsciousness on resting state brain connectivity, using graph analysis based on independent component analysis and a classical seed-based analysis. Contrary to previous propofol research, which mainly emphasized the importance of connectivity in the default mode network ...
متن کاملThalamocortical synchronization during induction and emergence from propofol-induced unconsciousness.
General anesthesia (GA) is a reversible drug-induced state of altered arousal required for more than 60,000 surgical procedures each day in the United States alone. Sedation and unconsciousness under GA are associated with stereotyped electrophysiological oscillations that are thought to reflect profound disruptions of activity in neuronal circuits that mediate awareness and cognition. Computat...
متن کاملNeural correlates of successful semantic processing during propofol sedation.
Sedation has a graded effect on brain responses to auditory stimuli: perceptual processing persists at sedation levels that attenuate more complex processing. We used fMRI in healthy volunteers sedated with propofol to assess changes in neural responses to spoken stimuli. Volunteers were scanned awake, sedated, and during recovery, while making perceptual or semantic decisions about nonspeech s...
متن کاملSequential effects of increasing propofol sedation on frontal and temporal cortices as indexed by auditory event-related potentials.
BACKGROUND It is an open question whether cognitive processes of auditory perception that are mediated by functionally different cortices exhibit the same sensitivity to sedation. The auditory event-related potentials P1, mismatch negativity (MMN), and early right anterior negativity (ERAN) originate from different cortical areas and reflect different stages of auditory processing. The P1 origi...
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ژورنال
عنوان ژورنال: Clinical Neurophysiology
سال: 2006
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2006.05.009