Auditory and Lower Limb Tactile Prepulse Inhibition in Primary Restless Legs Syndrome

Sensory profile in primary restless legs syndrome and restless legs syndrome associated with small fibre neuropathy.

Sir, The association of restless legs syndrome with polyneuropathy, especially with involvement of small sensory fibres, is suggested by several observations (Iannaccone et al., 1995; Polydefkis et al., 2000; Gemignani et al., 2006); however, it is still controversial (Hattan et al., 2009). Bachmann et al. (2010) investigated 34 consecutive outpatients with restless legs syndrome from their Mov...

Ropinirole in restless legs syndrome and periodic limb movement disorder

Dopaminergic agents, particularly dopamine agonists, have been used with increasing frequency in the treatment of restless legs syndrome and periodic limb movement disorder. These evidence-based practice parameters are complementary to the Practice Parameters for the Treatment of Restless Legs Syndrome and Periodic Limb Movement Disorder, published in 1999. These practice parameters were develo...

Restless Legs Syndrome Prevalence in Major Thalasemia Tabriz Children Hospital

Secondary periodic limb movement disorder and restless legs syndrome.

Periodic limb movement disorder (PLMD) and restless legs syndrome (RLS) are well-known entities from a clinical and polysomnographic point of view. PLMD and RLS are seen mostly as primary or hereditary diseases, but may occur in conjunction to other diseases such as uremia, polyneuropathy, Parkinson's disease, and deficiencies of iron and magnesium. This review will discuss the prevalence, etio...

The restless legs syndrome.

The first description of the restless legs syndrome (RLS) is attributed to Thomas Willis in the 'London Practice of Physick' of 1685 (Ekbom, 1960). Here he wrote 'wherefore to some, when being a bed they betake themselves to sleep, presently in the arms and leggs, leapings and contractions of their tendons, and so great a restlessness and tossings of their members ensue, that the diseased are n...