Atypical presentation of Monkeypox virus infection
نویسندگان
چکیده
A 69-year-old man was referred for a necrotic lesion on the nose suggestive of bacterial infection. The patient had HIV-positive status with normal CD4+ T-cell count and undetectable viral load. Despite antibiotic treatment, expanded, vesiculopustular lesions appeared legs hands. Monkeypox infection diagnosed by polymerase chain reaction swabs obtained from hands nose. This unusual presentation, cellulitis face, highlights importance extra-genital presentations
منابع مشابه
Inhalational monkeypox virus infection in cynomolgus macaques
An inhalation exposure system was characterized to deliver aerosolized monkeypox virus (MPXV), and a non-human primate (NHP) inhalation monkeypox model was developed in cynomolgus macaques. A head-only aerosol exposure system was characterized, and two sampling methods were evaluated: liquid impingement via an impinger and impaction via a gelatin filter. The aerosol concentrations obtained with...
متن کاملInhibition of cowpox virus and monkeypox virus infection by mitoxantrone.
Mitoxantrone, an FDA-approved therapeutic for the treatment of cancer and multiple sclerosis, was previously reported to exhibit antiviral activity against vaccinia virus. To determine whether this activity extends to other orthopoxviruses, mitoxantrone was tested against cowpox and monkeypox. Mitoxantrone demonstrated an EC(50) of 0.25 μM against cowpox and 0.8 μM against monkeypox. Intraperit...
متن کاملMonkeypox virus.
INTRODUCTION ......... ..................................... I HISTORICAL NOTE ........... ................................... 2 Recognition of Monkeypox in Nonhuman Primates ....... ..................... 2 Human Infection with Monkeypox Virus ..................................... 3 CLASSIFICATION .......... .................................... 3 MONKEYPOX VIRUS AS AN INFECTIOUS AGENT ...... .....
متن کاملExperimental Infection of Prairie Dogs with Monkeypox Virus
Studies of experimental infection of prairie dogs (Cynomys ludovicianus) with monkeypox virus are described. After intraperitoneal infection, all of the animals died within 11 days. Virus was cultured from their blood and oropharynx several days before death; at necropsy, most of the organs tested contained monkeypox virus. Marked hepatic and splenic necrosis were observed, along with mild infl...
متن کاملExperimental Infection of Ground Squirrels (Spermophilus tridecemlineatus) with Monkeypox Virus
A proposed new small-animal (rodent) model for studying the pathogenesis and treatment of severe orthopoxvirus infections is described. Thirteen-lined ground squirrels (Spermophilus tridecemlineatus) were infected intraperitoneally and intranasally with monkeypox virus (MPXV). A fulminant illness developed in all animals, and they died 6-9 days after infection. Virus was cultured from the blood...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: JEADV Clinical Practice
سال: 2023
ISSN: ['2768-6566']
DOI: https://doi.org/10.1002/jvc2.146