Atypical parkinsonism

Atypical parkinsonism: an update

PURPOSE OF REVIEW This update discusses novel aspects on genetics, diagnosis, and treatments of atypical parkinsonism published over the past 2 years. RECENT FINDINGS A genome-wide association study identified new genetic risk factors for progressive supranuclear palsy and new genetic conditions presenting with atypical parkinsonism have been described. The clinical criteria for diagnosis of ...

Atypical antipsychotics and parkinsonism.

BACKGROUND Atypical antipsychotic agents are thought to be less likely than older typical agents to produce parkinsonism. This has not been well documented. We compared the risk of development of incident parkinsonism among older adults dispensed atypical relative to typical antipsychotics. METHODS Retrospective cohort study of all adults 66 years and older in Ontario. We used Cox proportiona...

Genetics of Atypical Parkinsonism Implications for Nosology

Clinical features of dystonia in atypical parkinsonism.

BACKGROUND The association between Dystonia and Parkinson's disease (PD) has been well described especially for foot and hand dystonia. There is however few data on dystonic postures in patients with atypical parkinsonism. OBJECTIVE To evaluate the frequency and pattern of dystonia in a group of patients with atypical parkinsonism (multiple system atrophy - MSA, progressive supranuclear palsy...

Atypical parkinsonism and Annonaceae consumption in New Caledonia.

Recent studies have suggested a high incidence of atypical parkinsonism in patients living in or coming from different “exotic” areas.1–3 In some cases, environmental factors have been suspected, including the consumption of tropical fruits of the Annonaceae family containing alkaloids with possible neurological toxicity.1,4,5 Three Annonaceae fruits (Annona muricata, A. squamosa, and A. reticu...