Atypical HIV-vacuolar myelopathy: a case report

Abstract Background Here, we report an atypical HIV-vacuolar myelopathy and search the available medical literature about presentations of human immunodeficiency virus associate vacuolar (HIV-VM) immunoglobulin therapy response. Case A 26-year-old lady who was 4 weeks postpartum presented to us with acute flaccid quadriparesis, no sensory level. Extensive workup ruled out other causes myelopathy. She developed a stage 3 kidney injury, MRI showed diffuse cord atrophy involving lower cervical thoracic cord. The patient received IV-immunoglobulin, ARVs, supportive inadequate Unfortunately, she nosocomial pneumonia died. Discussion In HIV-VM, there is spinal atrophy, which mainly involves our case, this pathological process also affected cord's region, leading tetraplegia, high CD4 level, without response treatment, including intravenous immunoglobulin. Keynotes Vacuolar myelopathy, HIV, Immunoglobulin therapy, hypokalaemia. Renal failure.