Atypical Ductal Hyperplasia: Factors predicting upstaging to carcinoma
نویسندگان
چکیده
منابع مشابه
Ductal Epithelial Lesions: Ductal Carcinoma In Situ vs Atypical Ductal Hyperplasia vs Flat Epithelial Atypia
Before the era of mammography, ductal carcinoma in situ (DCIS) comprised only less than 3% of newly diagnosed breast cancers, most as large palpable masses, and many with microscopic foci of invasion. With widespread use of mammography, DCIS now makes up about 25% of breast cancers diagnosed in the U.S., most as non-palpable lesions. There is also concurrent increased prevalence of atypical duc...
متن کاملP63 and cytokeratin8/18 expression in breast, atypical ductal hyperplasia, ductal carcinoma in situ and invasive duct carcinoma.
Background and Purpose : The pattern and distribution of p63 expression as a myoepithelial/basal stem cell marker can be different between atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) and may denote basal phenotype of breast ductal carcinoma. CK8/18 is a luminal marker and may indicate a luminal phenotype of IDC and its expression in ADH...
متن کاملFactors predicting microinvasion in Ductal Carcinoma in situ.
BACKGROUND Whether sentinel lymph node biopsy (SLNB) should be performed in patients with pure ductal carcinoma in situ (DCIS) of the breast has been a question of debate over the last decade. The aim of this study was to identify factors associated with microinvasive disease and determine the criteria for performing SLNB in patients with DCIS. MATERIALS AND METHODS 125 patients with DCIS who...
متن کاملBorderline atypical ductal hyperplasia/low-grade ductal carcinoma in situ on breast needle core biopsy should be managed conservatively.
The differential diagnosis of low-nuclear grade intraductal epithelial proliferations of the breast includes atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DCIS). This distinction can be difficult on core needle biopsy (CNB) but can have significant clinical ramifications. We examined the clinical course of patients diagnosed on CNB with borderline ADH/DCIS lesions [marked ADH ...
متن کاملPredictive factors for breast cancer in patients diagnosed atypical ductal hyperplasia at core needle biopsy
BACKGROUND Percutaneous core needle biopsy (CNB) is considered to be the standard technique for histological diagnosis of breast lesions. But, it is less reliable for diagnosing atypical ductal hyperplasia (ADH). The purpose of the present study was to predict, based on clinical and radiological findings, which cases of ADH diagnosed by CNB would be more likely to be associated with a more adva...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Archives of Surgery and Clinical Research
سال: 2020
ISSN: 2576-9537
DOI: 10.29328/journal.ascr.1001045