منابع مشابه
Atypical Bacteria and Macrolides in Asthma
: Chlamydophila pneumoniae and Mycoplasma pneumoniae are common pathogens causing acute illness in both the upper and lower airways. Several observations are supportive of a possible causative role of these pathogens in asthma; however, more evidence is required before this becomes meaningful in clinical practice. Atypical bacteria can enhance airway hyperresponsiveness and inflammation, both o...
متن کاملMacrolides in the treatment of asthma.
PURPOSE OF REVIEW This review summarizes the importance of macrolide therapy in the treatment of asthma, discusses macrolide mechanisms of action, and outlines new clinical data supporting their use. The effects of macrolides on both the innate and adaptive immune responses are discussed. RECENT FINDINGS Subacute bacterial infection with both typical and atypical organisms contributes to poor...
متن کاملRole of viruses and atypical bacteria in asthma exacerbations among children in Oporto (Portugal).
BACKGROUND Upper respiratory tract infections are known to be a significant precipitant of acute asthma exacerbations. The aim of this study was to evaluate seasonal trends and the role of these pathogens in asthma exacerbations in school-aged children from Oporto (Portugal). METHODS Nasal aspirates were collected from children aged 6 to 12 years old with asthma exacerbations attended in the ...
متن کاملRespiratory viruses and atypical bacteria triggering severe asthma exacerbation in children.
1. Respiratory viruses and atypical bacteria were detected in 51.0% of Hong Kong children with asthma exacerbations, which was significantly higher than the detection rate of 27.3% in children with chronic stable asthma. 2. Co-infections of two or more respiratory pathogens were more commonly found in children with asthma exacerbations (10.7%) than in patients with stable asthma (2.6%). 3. Huma...
متن کاملMacrolides for the treatment of chronic sinusitis, asthma, and COPD.
In addition to their well-known antimicrobial activity, macrolides possess immunomodulatory properties that may confer beneficial effects to patients with respiratory diseases associated with chronic inflammation. These properties include attenuation of inflammatory responses in the lung, mucoregulatory properties, and effects on bronchial responsiveness. Macrolides increase mucociliary clearan...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Allergy, Asthma & Clinical Immunology
سال: 2008
ISSN: 1710-1492
DOI: 10.1186/1710-1492-4-3-111