منابع مشابه
Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia.
Infusion rates for atracurium were calculated from multiple bolus injection data for normothermic (38 degrees C; n = 4) and hyperthermic (42 degrees C; n = 14) dogs anesthetized with thiopental and oxymorphone while undergoing whole-body hyperthermia treatment. The calculated infusion rate for atracurium at 38 degrees C was 6.2 +/- 0.3 micrograms/kg/min and the calculated infusion rate at 42 de...
متن کاملWhole-Body Hyperthermia Induction Techniques1
Currently, there are three techniques used for delivery of whole-body hyperthermia. The simplest of these is direct contact between skin and some surrounding fluid. The surrounding fluid can be either water, wax, air, or other fluid medium; heat is transferred from the surrounding fluid to the body surface. Ves sels in the skin surface transfer heat to the perfusing blood, which uniformly distr...
متن کاملProtocol for long duration whole body hyperthermia in mice.
Hyperthermia is a general term used to define the increase in core body temperature above normal. It is often used to describe the increased core body temperature that is observed during fever. The use of hyperthermia as an adjuvant has emerged as a promising procedure for tumor regression in the field of cancer biology. For this purpose, the most important requirement is to have reliable and u...
متن کاملSplanchnic tissues undergo hypoxic stress during whole body hyperthermia.
Exposure of conscious animals to environmental heat stress increases portal venous radical content. The nature of the observed heat stress-inducible radical molecules suggests that hyperthermia produces cellular hypoxic stress in liver and intestine. To investigate this hypothesis, conscious rats bearing in-dwelling portal venous and femoral artery catheters were exposed to normothermic or hype...
متن کاملPhysiological Studies of Whole-Body Hyperthermia of Dogs1
Whole body hyperthermia to 42°Cwas induced in five normal beagles, using a humidityand temperature-controlled chamber. Core temperatures of 41.2-43.0°C were achieved in 50 min and maintained for 60 min. Cardiopulmonary responses included marked tachypnea and tachycardia. Blood gases underwent progressive drops in both PO2(mean, 117 torr) and PC02 (mean, 22 torr), suggesting the possibility of...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1990
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1990.tb14654.x