ATP-Sensitive Potassium Channels Regulate In Vivo Dopamine Release in Rat Striatum
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چکیده
منابع مشابه
Adenosine and ATP-sensitive potassium channels modulate dopamine release in the anoxic turtle (Trachemys scripta) striatum.
Excessive dopamine (DA) is known to cause hypoxic/ischemic damage to mammalian brain. The freshwater turtle Trachemys scripta, however, maintains basal striatal DA levels in anoxia. We investigated DA balance during early anoxia when energy status in the turtle brain is compromised. The roles of ATP-sensitive potassium (K(ATP)) channels and adenosine (AD) receptors were investigated as these fa...
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متن کاملAnti-nociceptive effect of cimetidine in mice: the role of ATP-sensitive potassium channels
Recent studies have shown that intracerebroventricular administration of cimetidine (CIM) induces anti-nociceptive and anti–inflammatory effects in rats. However, the underlying mechanism of CIM effect has not been determined yet. This study was planned to determine the anti-nociceptive effect of CIM (50 mg/kg, i.p.) in male mice (25-30 g, n = 80) using tail flick test. Also, the role of ATP-se...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1999
ISSN: 0021-5198
DOI: 10.1254/jjp.79.59