Atopic dermatitis and vitamin D: facts and controversies

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Atopic dermatitis and vitamin D: facts and controversies*

Patients with atopic dermatitis have genetically determined risk factors that affect the barrier function of the skin and immune responses that interact with environmental factors. Clinically, this results in an intensely pruriginous and inflamed skin that allows the penetration of irritants and allergens and predisposes patients to colonization and infection by microorganisms. Among the variou...

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Vitamin D and Atopic Dermatitis in Childhood

Vitamin D features immunomodulatory effects on both the innate and adaptive immune systems, which may explain the growing evidence connecting vitamin D to allergic diseases. A wealth of studies describing a beneficial effect of vitamin D on atopic dermatitis (AD) prevalence and severity are known. However, observations linking high vitamin D levels to an increased risk of developing AD have als...

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Vitamin D and atopic dermatitis: association, causation, or confusion?

To the Editor, We read with interest the recent article by Wang et al. (1) that reported a potential association between vitamin D deficiency and severity of atopic dermatitis (AD) in children in Hong Kong. This subject is topical and studies to date that have investigated a potential link between the two have yielded contradictory findings. Although the study by Wang et al. has some merits, we...

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Heliotherapy improves vitamin D balance and atopic dermatitis.

BACKGROUND Vitamin D insufficiency during winter is common in the Nordic countries. Heliotherapy (HT) may heal atopic dermatitis (AD) but its effect on vitamin D balance has not been examined. OBJECTIVES To study the effect of HT on serum calcidiol (25-hydroxyvitamin D) concentration and on healing of AD. METHODS Twenty-three adult patients with AD received a 2-week course of HT in the Cana...

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Seborrheic dermatitis: etiology, risk factors, and treatments: facts and controversies.

Seborrheic dermatitis (SD) is a common skin condition seen frequently in clinical practice. The use of varying terms such as sebopsoriasis, seborrheic dermatitis, seborrheic eczema, dandruff, and pityriasis capitis reflects the complex nature of this condition. Despite its frequency, much controversy remains regarding the pathogenesis of SD. This controversy extends to its classification in the...

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ژورنال

عنوان ژورنال: Anais Brasileiros de Dermatologia

سال: 2013

ISSN: 0365-0596

DOI: 10.1590/abd1806-4841.20132660