Atomic Force Microscopy of DNA-CTAB Aggregates

Automated DNA Sizing by Atomic Force Microscopy

W a) " NA sizing is one of the most widely used analytical methods in molecular _6 42 biology and biochemistry, and it is a core method for genomic analysis. Many research, • toE health care, and forensic applications rely on DNA sizing. Given the volume of DNA C: sizing done and the associated cost, an increasing need exists for extremely rapid, high. throughput, and inexpensive techniques. Es...

Atomic Force Microscopy Application in Biological Research: A Review Study

Atomic force microscopy (AFM) is a three-dimensional topographic technique with a high atomic resolution to measure surface roughness. AFM is a kind of scanning probe microscope, and its near-field technique is based on the interaction between a sharp tip and the atoms of the sample surface. There are several methods and many ways to modify the tip of the AFM to investigate surface properties, ...

Sub-diffraction imaging of huntingtin protein aggregates by fluorescence blink-microscopy and atomic force microscopy.

Noncontact atomic force microscopy

No other method has opened the door to progress in nanoscience and nanotechnology as much as the introduction of scanning probe methods did in the 1980s, since they offer a way to visualize the nanoworld. For maximum impact, however, the ability to image and manipulate individual atoms is the key. Initially, scanning tunneling microscopy was the only scanningprobe-based method that was able to ...

Intermodulation atomic force microscopy

A mode of atomic force microscopy AFM is demonstrated where an oscillating AFM cantilever having linear response is driven with two frequencies in the vicinity of a resonance. New frequencies in the response, known as intermodulation products, are generated when the linearity of the cantilever response is perturbed by the nonlinear tip-surface interaction. A rich structure of the intermodulatio...