منابع مشابه
Atherogenic dyslipidemia and the metabolic syndrome.
INTRODUCTION High serum cholesterol has been known as being a main risk factor for coronary heart disease (CHD). A number of types of evidence support the cholesterol-CHD link, these include researches in laboratory animals, epidemiological studies, findings of premature CHD in genetic forms of hypercholesterolemia, laboratory investigations, and clinical trials of cholesterol-lowering therapy....
متن کاملDietary and genetic probes of atherogenic dyslipidemia.
A goal of dietary management of cardiovascular disease risk in patients with obesity and metabolic syndrome is improvement in the atherogenic dyslipidemia comprising elevated triglyceride, reduced high-density lipoprotein (HDL) cholesterol, and increased numbers of small, dense low-density lipoprotein (LDL) particles. Individuals with a genetically influenced trait characterized by a high propo...
متن کاملThe metabolic basis of atherogenic dyslipidemia.
Atherogenic dyslipidemia is one of the major components of the metabolic syndrome, a complex cluster of several risk factors within a single patient that according to the National Cholesterol Education Program (NCEP) Adult Treatment Panel III includes at least 3 of the following: large waist circumference, elevated triglyceride levels, low levels of high-density lipoprotein cholesterol (HDL-C),...
متن کاملCRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia
With atherosclerotic vascular disease being the leading cause of death in the United States and worldwide, enormous effort has been focused on understanding the development and progression of disease, with an eye toward improving the prevention and treatment of disease. In just the last decade, genotyping and sequencing studies have considerably expanded our knowledge of how genetic variation i...
متن کاملAdipocyte Triglyceride Turnover Is Independently Associated With Atherogenic Dyslipidemia
BACKGROUND Inappropriate storage of fatty acids as triglycerides in adipocytes and their removal from adipocytes through lipolysis and subsequent oxidation may cause the atherogenic dyslipidemia phenotype of elevated apolipoprotein B levels and subsequent hypertriglyceridemia. We tested whether turnover of triglycerides in fat cells was related to dyslipidemia. METHODS AND RESULTS The age of ...
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ژورنال
عنوان ژورنال: Indian Journal of Endocrinology and Metabolism
سال: 2013
ISSN: 2230-8210
DOI: 10.4103/2230-8210.122600