Asymmetric membrane capsule for osmotic delivery of flurbiprofen
نویسندگان
چکیده
منابع مشابه
Asymmetric Membrane Capsule (amc): an Useful Osmotic Drug Delivery System
Osmotic drug delivery mechanism is well known in the field of oral controlled release systems. The release of drug from the osmotic drug delivery devices is based on the phenomenon of osmosis. An useful technology developed for osmotic delivery of drug is asymmetric membrane capsule (AMC), which is an economic and effective drug delivery device as compared to other existing technique of osmotic...
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The aim of the present study was to design an asymmetric membrane capsule, an osmotic pump-based drug delivery system of ethyl cellulose for controlled release of terbutaline sulphate. asymmetric membrane capsules contains pore-forming water soluble additive, sorbitol in different concentrations in the capsule shell membrane, which after coming in contact with water, dissolves, resulting in an ...
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Hard gelatin capsule filled with acetaminophen, osmotic agent (sorbitol), a release promoter (sodium dodecyl sulfate), coated with a semipermeable cellulose acetate membrane containing a hydrophobic plasticizer (castor oil) and sealed with white bees wax plug was designed. When placed in the sink water penetrates the membrane, dissolves the osmotic agent and increases the osmotic pressure...
متن کاملMetal organic frameworks as a drug delivery system for flurbiprofen
BACKGROUND Metal organic frameworks (MOFs) have attracted more attention in the last decade because of a suitable pore size, large surface area, and high pore volume. Developing biocompatible MOFs such as the MIL family as a drug delivery system is possible. PURPOSE Flurbiprofen (FBP), a nonsteroidal anti-inflammatory agent, is practically insoluble in aqueous solution, and, therefore, needs ...
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Akin type (asymmetric) reverse osmosis membranes undergo an irreversible osmotic dehydration upon coming into contact (skin side) with salt solutions. The extent of consequent changes (in appearance; decrease in linear dimension, water flux and salt rejection) are dependent on the salt concentration. These observations are correlated with the expected morphological changes taking place duri...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2007
ISSN: 1846-9558,1330-0075
DOI: 10.2478/v10007-007-0027-3