منابع مشابه
Asymmetric Hydrogenation
The asymmetric hydrogenation of prochiral unsaturated compounds, such as alkenes, ketones, and imines, is one of the most efficient and straightforward methods for the preparation of optically active compounds. This method uses dihydrogen and small amounts of chiral transition metal complexes and is now recognized as economical, operationally simple, and environmentally friendly. It is frequent...
متن کاملAsymmetric Hydrogenation and Transfer Hydrogenation of Ketones
Optically active alcohols are important building blocks in the synthesis of fine chemicals, pharmaceuticals, agrochemicals, flavors and fragrances as well as functional materials (Arai & Ohkuma, 2011; Klingler, 2007). Furthermore, molecular hydrogen is without doubt the cleanest reducing agent, with complete atom efficiency. Therefore, the catalytic, asymmetric hydrogenation (AH) of prochiral k...
متن کاملAsymmetric Hydrogenation Catalysts
Iridium complexes with chiral N,P ligands have established themselves as efficient catalysts for the asymmetric hydrogenation of olefins, with largely complementary scope to Rh and Ru diphosphane complexes. In contrast to Rh and Ru catalysts, they do not require a coordinating polar group next to the C=C bond. Initial experiments with cationic phosphanyloxazoline (phox) complexes ([Ir(1)(cod)]X...
متن کاملCatalytic asymmetric hydrogenation of naphthalenes.
The catalytic asymmetric hydrogenation of heteroarenes has been intensively studied during the last decade. Nowadays, various heteroaromatics, for example, indoles, pyrroles, and quinolines, can be reduced to the corresponding chiral heterocycles with high stereoselectivity through asymmetric catalysis. Glorius and co-workers recently found that a chiral N-heterocyclic carbene–ruthenium catalys...
متن کاملCatalytic Asymmetric Hydrogenation of Heteroarenes
INTRODUCTION Asymmetric hydrogenation of unsaturated organic compounds has been established as one of the most efficient methods for the preparation of chiral, non-racemic substrates. Among hydrogenation of various substrates, the asymmetric hydrogenation of heteroarenes provides a straightforward approach to a wide range of enantiomerically pure saturated heterocycles, which are subunits of ma...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1959
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.17.640