Asymmetric Cell Division: A Persistent Issue?
نویسندگان
چکیده
منابع مشابه
Asymmetric cell division: a persistent issue?
Heterogeneity within a clonal population of cells can increase survival in the face of environmental stress. In a recent issue of Science, Aldridge et al. (2012) demonstrate that cell division in mycobacteria is asymmetric, producing daughter cells that differ in size, growth rate, and susceptibility to antibiotics.
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Cell divisions producing two daughter cells that adopt distinct fates are defined as asymmetric. In all organisms, ranging from bacteria to mammals, in which development has been studied extensively, asymmetric cell divisions generate cell diversity. Asymmetric cell divisions can be achieved by either intrinsic or extrinsic mechanisms (Fig. 1). Intrinsic mechanisms involve the preferential segr...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2012
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2012.01.016