Assortment of kaempferol and zinc gluconate improves noise-induced biochemical imbalance and deficits in body weight gain

Abstract This study investigated the effects of pretreatment with antioxidants, kaempferol, and zinc gluconate on serum biochemical changes impairment in body weight gain following noise-exposure Wistar rats. Thirty-five animals were evenly grouped into five cohorts: Groups II, III, IV, V exposed to noise stress, induced by exposing rats 100 dB (4 hr/day) for 15 days, from days 33 48 after starting drug treatments. Treatment kaempferol and/or mitigated noise-induced deficits gain, levels lipid protein fractions. The combined treatment significantly ( p < .05) decreased malondialdehyde concentration + treated group, compared group administered deionized water noise. result demonstrates that dyshomeostasis peroxidation may be involved molecular mechanism underlying stress assortment produced an improved mitigating outcome