Association of Moderate Hypothermia at Admission with Short-Term and Long-Term Outcomes in Extremely Low Birth Weight Infants

Purpose: Extremely low birth weight (ELBW) infants exhibit immature thermoregulation and are easily exposed to hypothermia. We investigated the association between hypothermia on admission with short- long-term outcomes.Methods: Medical records of ELBW admitted neonatal intensive care unit a tertiary medical center June 2012 February 2017 were retrospectively analyzed. Upon admission, axillary body temperature was measured. Moderate defined as below 36 ℃.Results: A total 208 gestational age 26.4±2.3 weeks 746.7±154.9 g included. Admission ranged from 33.5 36.8 ℃ (median 36.1 ℃). Univariate analyses maternal infant characteristics performed for moderately hypothermic control (normothermic mildly hypothermic) infants. Lower age, lower weight, vaginal delivery correlated moderate Logistic regression adjusted confounders revealed that incidence hemodynamically significant patent ductus arteriosus (hsPDA) associated in Moreover, abnormal mental developmental index scores Bayley Scales Infant Development II at corrected 18 24 months hypothermia, but not psychomotor index, blindness, deafness, or cerebral palsy.Conclusion: is only short-term morbidities such hsPDA, may also be neurodevelopmental impairment Future large-scale studies required clarify consequences upon admission.