Association of malnutrition with in-hospital and long-term outcomes among ST-elevation myocardial infarction patients receiving primary PCI

Abstract Background The impact of malnutrition on outcomes in a contemporary ST-segment-elevation myocardial infarction (STEMI) population is unclear. We hypothesized that severity amongst STEMI patients undergoing primary percutaneous coronary intervention (pPCI) associated with worse long-term outcomes. Purpose aim this study was 2-fold: 1) to establish the prevalence among pPCI; 2) determine association in-hospital and 1-year receiving pPCI Methods retrospectively identified 1,169 age ≥65 years who had received (2013–2020). Patients presented out-of-hospital cardiac arrest or those fibrinolytic therapy were excluded. Controlling Nutritional Status (CONUT) score, based serum albumin, total cholesterol lymphocyte count, used as tool assess nutritional status included patients. Malnourished defined CONUT score 5 12. To account for frailty, frailty index (FI) determined using health deficit accumulation model (Table 1). outcome all-cause mortality. secondary composite heart failure, cardiogenic shock, re-infarction, major bleeding, stroke, A multivariable adjusting baseline covariates, including performed (Figure Results Among pPCI, 315 (26.9%) classified malnourished. older (mean 77.4 vs. 76.0 years, p=0.009) higher comorbidity burden. After adjustment, worsening increased mortality (odds ratio [OR] = 1.29, p<0.001). Worsening also incidence adverse (OR 1.12, p=0.003) (OR=1.41, Conclusion 1 4 Malnutrition rate outcomes, even when accounting frailty. Efforts routinely identify malnourished implement best practices reduce risk events vulnerable are warranted. Funding Acknowledgement Type funding sources: None.