Association between synovial fluid prostanoid levels and ultrasonographic findings in knee osteoarthritis

Purpose. The aim of this study was to investigate the association between prostanoid [thromboxane (TxA2) and prostacyclin (PGI2)] levels in synovial fluid infrapatellar fat pad (IPFP)/ suprapatellar (SPFP) thickness as well other clinical findings knee steoarthritis (OA) patients.
 Materials Methods: 16 patients with OA effusion were included. average pain evaluated using a Visual Analogue Scale (VAS). pain, stiffness, physical functions Western Ontario McMaster Universities Osteoarthritis Index (WOMAC). 6-keto-PGF1α, stable metabolite PGI2, TxB2, TxA2, measured an enzyme immunoassay.
 Results: 6-keto-PGF1α significantly greater than TxB2 OA. TxB2/6-keto- PGF1α ratio negatively correlated SPFP cartilage thickness, respectively. IPFP positively volume. WOMAC scores VAS-activity VAC-evening scores.
 Conclusion: In comparison 6-keto- fluid, seem be more associated ultrasonographic