Association between Serum Cytokeratin-18 Neoepitope M30 (CK-18 M30) Levels and Chronic Hepatitis B: A Meta-Analysis
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منابع مشابه
The Clinical Significance of Serum Apoptotic Cytokeratin 18 Neoepitope M30 (CK-18 M30) and Matrix Metalloproteinase 2 (MMP-2) Levels in Chronic Hepatitis B Patients with Cirrhosis
BACKGROUND Serum apoptotic cytokeratine 18 neoepitope M30 (CK-18 M30) and matrix metalloproteinase 2 (MMP-2) have been popular markers for detecting liver fibrosis in recent years. CK-18 is a major intermediate filament protein in liver cells and one of the most prominent substrates of caspases during hepatocyte apoptosis. MMP-2 plays an important role in tissue remodeling and repairing process...
متن کاملthe clinical significance of serum apoptotic cytokeratin 18 neoepitope m30 (ck-18 m30) and matrix metalloproteinase 2 (mmp-2) levels in chronic hepatitis b patients with cirrhosis
background serum apoptotic cytokeratine 18 neoepitope m30 (ck-18 m30) and matrix metalloproteinase 2 (mmp-2) have been popular markers for detecting liver fibrosis in recent years. ck-18 is a major intermediate filament protein in liver cells and one of the most prominent substrates of caspases during hepatocyte apoptosis. mmp-2 plays an important role in tissue remodeling and repairing process...
متن کاملSerum Cytokeratin 18 M30 Levels in Chronic Hepatitis B Reflect Both Phase and Histological Activities of Disease
Chronic hepatitis B has highly a dynamic course with significant fluctuations of HBV-DNA and ALT impeding assessment of disease activity. New biomarkers of inflammatory versus noninflammatory stages of HBV infection are urgently needed. Cytokeratin 18 epitope M30 (M30 CK-18) is a sensitive marker of cell death. We aimed to investigate an association between serum M30 CK-18 and histological acti...
متن کاملclinical values of elevated serum cytokeratin-18 levels in hepatitis: a meta-analysis
conclusions serum ck-18 levels in hepatitis patients were higher, compared with healthy controls. our results revealed the clinical values of ck-18, in combination with other apoptosis markers, in identifying the development of hepatitis. background as an important intermediate filament protein within liver cells, cytokeratin-18 (ck-18) has been confirmed as a potential indicator in various hep...
متن کاملClinical Values of Elevated Serum Cytokeratin-18 Levels in Hepatitis: A Meta-Analysis
BACKGROUND As an important intermediate filament protein within liver cells, cytokeratin-18 (CK-18) has been confirmed as a potential indicator in various hepatitis progressions. OBJECTIVES We sought to clarify the connection between serum CK-18 levels and hepatitis pathogenesis in the present meta-analysis. MATERIALS AND METHODS With the application of various computerized databases, inclu...
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ژورنال
عنوان ژورنال: Hepatitis Monthly
سال: 2018
ISSN: 1735-143X,1735-3408
DOI: 10.5812/hepatmon.64152