Association between i.v. thrombolysis volume and door-to-needle times in acute ischemic stroke
نویسندگان
چکیده
منابع مشابه
Improving Door-to-Needle Times for Acute Ischemic Stroke
Faster treatment with intravenous alteplase (tissue-type plasminogen activator) results in better outcomes. Although the benchmark door-to-needle time (DTN) has been set at 60 minutes, many centers have been able to exceed this benchmark with median times from 20 to 51 minutes. These local efforts have been supported by national and international efforts to reduce DTN time. For example, the Ame...
متن کاملSymptom-to-needle Times in Acute Ischemic Stroke and Its Prehospital Related Factors
Background: Intravenous (IV) recombinant tissue Plasminogen Activator (rtPA) (IV-rtPA) is the only FDA-approved pharmacological therapy for treatment in acute ischemic stroke and the administration of IV-rtPA is crucially time-dependent. Objectives: This study aimed to evaluate symptom-to-needle time and factors associated with the prehospital delay in patients with acute ischemic stroke refer...
متن کاملShort Door-to-Needle Times in Acute Ischemic Stroke and Prospective Identification of Its Delaying Factors
BACKGROUND The clinical benefit of intravenous thrombolysis (IVT) in acute ischemic stroke is time dependent. Several studies report a short median door-to-needle time (DNT; 20 min), mainly in large tertiary referral hospitals equipped with a level 1 emergency department, a dedicated stroke team available 24/7, and on-site neuroimaging facilities. Meanwhile, in daily practice, the majority of s...
متن کاملDoor-to-needle times in acute ischemic stroke: how low can we go?
Neurology® 2012;79:1 IV human recombinant tissue plasminogen activator (rt-PA) is the best proven and most effective treatment for acute ischemic stroke. The benefits of rt-PA are highly dependent on the time elapsed since stroke symptoms.1 Accordingly, the Brain Attack Coalition recommends that the time from emergency room arrival to initiation of rt-PA (that is, the “door-toneedle” time) shou...
متن کاملReduction in IV t-PA door to needle times using an Acute Stroke Triage Pathway.
OBJECTIVE To determine the effectiveness of an Acute Stroke Triage Pathway in reducing door to needle times in acute stroke treatment with IV t-PA. BACKGROUND A previous study at our tertiary referral centre, examining IV t-PA door to needle times, was completed in 2000. The median door to needle time was beyond the recommended National Institute for Neurological Disorders and Stroke (NINDS) ...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2016
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s00415-016-8076-5