Association between atherogenic index of plasma and in-hospital mortality in patients with STEMI undergoing primary percutaneous coronary intervention

Aim: Dyslipidemia is an established risk factor for cardiovascular disease. Increased triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) levels, and decreased high (HDL-C) levels were associated with increased risk. Recently, comprehensive lipid profile indices derived from these conventional parameters have attracted to attention. Atherogenic index of plasma (AIP) one the calculated as logarithm TG/HDL-C it accepted alternative simple marker atherogenicity. Although various studies demonstrated that their relationship clinical outcomes in patients acute coronary syndrome, this situation not yet clear ST-elevation myocardial infarction (STEMI) undergoing primer percutaneous intervention (pPCI). In study, we aimed investigate AIP early mortality STEMI pPCI.Material Method: This a retrospective, single center, hospital-based study carried out between January 2019 April 2021. A total 873 consecutive (705 men; median age 59 years), whose pPCI, enrolled. The divided into two groups according in-hospital status namely survivors vs non-survivors. Conventional values measured non-traditional indexes including non-HDL-C [Total minus HDL-C], Total cholesterol/HDL-C, LDL-C/HDL-C, atherogenic (AI) [non-HDL-C/HDL-C], combine (LCI) cholesterol*TG*LDL-C/HDL-C] [Log(TG/HDL-C)] calculated. Angiographic images evaluated through hospital automation system. Results: was significantly higher non-survivors compared survivor group (0.59, 0.47, p=0.006, respectively). AI, non-HDL-C, cholesterol/HDL-C ratio, LDL-C/HDL-C ratio LCI measurements similar groups. cut-off value (0.50) 70% sensitivity 52% specificity predicts mortality. Multivariate logistic regression model indicated (OR: 3.77, 95% CI: 1.34–10.6, p < 0.012) independent predictor pPCI. Conclusion: AIP, which can be easily by complete blood beneficial evaluating prognosis patients.