Association between APOE polymorphisms and lipid profile in Mexican Amerindian population

Association between Cytochrome P450 2C19 Gene Polymorphisms and Hematological Malignancies in an Iranian Population

Background: Cytochrome P450 2C19 (CYP2C19) is widely involved in the metabolism of some medications. On the other hand, recent studies have shown the contribution of the CYP2C19 polymorphisms to different malignancies. We aimed to investigate the association between CYP2C19 polymorphism and occurrence of hematological malignancies by comparing the phenotype distribution of this enzyme in patien...

The Association between TNF-alpha Gene Polymorphisms and Endometriosis in An Iranian Population

Objective Objective: TNF-α is an important cytokine in acute inflammatory response to infective factors. It seems that this response increases in patients with endometriosis due to presence of cytokines such as TNF-α which has been investigated in patients with endometriosis in different populations. This study aimed at examining four polymorphisms; TNF-α -238G/A, -308G/A, -857C/T and -863C/A a...

the association between sporadic alzheimer’s disease and the human abca1 and apoe gene polymorphisms in iranian population

Polymorphisms in PPARG and APOE: relationships with lipid profile of adolescents with cardiovascular risk factors

Background: Cardiovascular diseases constitute the main death cause worldwide resulting from a combination of genetic and lifestyle factors, and the prevalence among younger individuals has increased. It is important to early identify changes in lipid profile and the influence of genetic variations in specific genes on the individual patterns of lipid profile. Thus, the aim of this study was to...

Assessing the Association Between Fennel (Foeniculum Vulgare) Extract and Serum Lipid Profile and Leptin Receptor Expression

Introduction:Obesity is one of the most serious challenges of our era, with significant health consequences and high economic burden for health systems. Therefore, many countries have developed political agendas to cope with this ever-rising challenge. Along with chemical medications that are developed to manage obesity, researchers have focused on some natural ingredients and herbal extracts w...