Association between alcohol-induced erythrocyte membrane alterations and hemolysis in chronic alcoholics
نویسندگان
چکیده
منابع مشابه
Association between alcohol-induced erythrocyte membrane alterations and hemolysis in chronic alcoholics
The present study aimed to understand the association between erythrocyte membrane alterations and hemolysis in chronic alcoholics. Study was conducted on human male volunteers aged between 35-45 years with a drinking history of 8-10 years. Results showed that plasma marker enzymes AST, ALT, ALP and γGT were increased in alcoholic subjects. Plasma and erythrocyte membrane lipid peroxidation, er...
متن کاملChanges in composition and properties of erythrocyte membrane in chronic alcoholics.
AIMS AND METHODS Alterations in cholesterol and phospholipid contents as well as fluidity and lipid peroxidation in erythrocyte membranes from chronic alcoholic humans were investigated. RESULTS While an increase in cholesterol with no change in phospholipid content was observed in erythrocyte membranes, the phospholipid content increased with no change in cholesterol in plasma. CONCLUSIONS...
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A patient with xerocytosis was found to have swimming-induced intravascular hemolysis and shortening of erythrocyte life-span. In a microviscometer, xerocytes were more susceptible than normal erythrocytes to hemolysis by shear stress. Fractionation of normal and abnormal cells on discontinuous Stractan density gradients revealed that increasingly dehydrated cells were increasingly more shear s...
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Erythrocytes have been long considered as "dead" cells with transport of oxygen (O(2)) as their only function. However, the ability of red blood cells (RBCs) to modulate the microcirculation is now recognized as an important additional function. This capacity is regulated by a key element in the rheologic process: the RBC membrane. This membrane is a complex unit with multiple interactions betw...
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ژورنال
عنوان ژورنال: Journal of Clinical Biochemistry and Nutrition
سال: 2017
ISSN: 0912-0009,1880-5086
DOI: 10.3164/jcbn.16-16