Assessment of the Effect of Multidrug Resistance Clostridium difficile Clinical Strains on the Dynamics of Clostridium difficile Infection Rate at Pediatric Oncological Hospital

Relevance. At the children's oncological hospital guidelines to treat patients with several groups of antibiotics at same time, which ensures formation multi-resistant strains Clostridium difficile, have a selective advantage for difficile infection developing, and also cause epidemics /or in associating an increase severity – infection. Aims. Multidrug resistance rate pediatric hospital. Results. An investigation carried out among children 143 toxigenic are resistant moxifloxacin 72.41%, clindamycin 63.72%, rifampicin 35.54%, tetracycline 26.45%, tigecycline 11.42%, vancomycin 4.4%, metronidazole 3.9%. multidrug-resistant proportion note level 3–4% per year. However, remained 0.4% 3.1% downward trend. As result, statistical calculations showed absence correlation between multidrug morbidity. Conclusions. Detection microorganisms proves need further study this problem Russia advisability monitoring hospitals.