Assessment of Corneal Stromal Remodeling and Regeneration after Photorefractive Keratectomy
نویسندگان
چکیده
منابع مشابه
Corneal Regeneration After Photorefractive Keratectomy: A Review.
Photorefractive keratectomy (PRK) remodels corneal stroma to compensate refractive errors. The removal of epithelium and the ablation of stroma provoke the disruption of corneal nerves and a release of several peptides from tears, epithelium, stroma and nerves. A myriad of cytokines, growth factors, and matrix metalloproteases participate in the process of corneal wound healing. Their balance w...
متن کاملComparison of stromal remodeling and keratocyte response after corneal incision and photorefractive keratectomy.
PURPOSE We investigated the keratocyte response and stromal remodeling after corneal incision and photorefractive keratectomy to understand the histophysiological and immunohistochemical differences between these two types of surgery. METHODS Corneal incision or photorefractive keratectomy was performed in rabbits or rats. Then we chronologically observed the histological changes and the chan...
متن کاملCorneal ectasia after photorefractive keratectomy.
Two patients developed corneal ectasia after photorefractive keratectomy (PRK). Case 1 had evidence of early keratoconus preoperatively, with manifest refractions of -4.00 +2.50 x 160 (20/20) in the right eye and -7.00 +3.00 x 180 (20/30) in the left eye; thin corneas (472 microm and 441 microm, respectively); and inferior paracentral steepening in the right eye and central steepening in the le...
متن کاملCorneal Epithelial Remodeling and Its Effect on Corneal Asphericity after Transepithelial Photorefractive Keratectomy for Myopia
Purpose. To evaluate the changes in epithelial thickness profile following transepithelial photorefractive keratectomy (T-PRK) for myopia and to investigate the effect of epithelial remodeling on corneal asphericity. Methods. Forty-four patients (44 right eyes) who underwent T-PRK were retrospectively evaluated. Epithelial thickness was measured using spectral-domain optical coherence tomograph...
متن کاملTopical combination of NGF and DHA increases rabbit corneal nerve regeneration after photorefractive keratectomy.
PURPOSE To investigate the effect of nerve growth factor (NGF) in combination with docosahexaenoic acid (DHA) on corneal nerve regeneration in a rabbit model after PRK and correlate the findings with functional tear test. METHODS Unilateral PRK was performed on 21 New Zealand albino rabbits. Three groups, each consisting of six rabbits, were randomized to receive twice-weekly treatments with ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-30372-2