Assessment, Ethics, and the Randomized Controlled Trial

The Effect of The Cognitive Behavioral Therapy and Pharmacotherapy on Infertility Stress:A Randomized Controlled Trial

Comparative clinical assessment of two nasolabial hyaluronic acid fillers: A double-blind, randomized controlled trial

Background: Various fillers have been used for the correction of nasolabial folds. This study investigated the efficacy and safety assessment of two hyaluronic acid (HA) fillers on moderate nasolabial folds. Methods: This study randomized 10 volunteers, aged 35 to 49 years, with moderate nasolabial folds. Volunteers received injections of HA A and HA B gels into the right or left skin folds. Th...

The Effect of Reflexology on Labor Pain and Length Among Primiparous Women: A Randomized Controlled Trial

Background: Pain control is considered as the key issue in modern midwifery. Along with medical painkillers, reflexology is viewed as a non-medical and noninvasive method. Hence, we aimed to investigate the effect of reflexology on the intensity of pain and length of labor. Materials and Methods: In this clinical trial, participants included 240 Iranian primiparous women with term and singleton...

P-70: Ultrasound Guided Artificial Insemination:A Randomized Controlled Trial

Background: To ascertain whether using ultrasound guidance during intrauterine insemination (IUI) could increase pregnancy rates. Materials and Methods: The population under study consisted of 73 consecutive couples subjected to IUI in our Human Reproduction Unit, between September and December 2006, with a total of 231 IUI cycles performed. The patients were randomized using a computer-generat...

Revisiting the Randomized Controlled Trial

Randomized controlled trial (RCT) is generally considered to be one of the strongest study designs because the results it generates, have minimum bias and avoids confounders by virtue of the randomization and blinding technique which it employs. It has the potential to generate a Level B evidence on its own or even a Level A evidence when a pooled meta-analysis or a systematic review of several...