منابع مشابه
The "FDA approval defense": penetrating the protective shield.
Pharmaceutical manufacturers decry the purported burdens imposed by Federal regulation when it suits their proprietary interests, yet they sing a wholly different tune when defending product liability suits. As product liability defendants, they unabashedly seek the protective womb of Food and Drug Administration (FDA) regulation, arguing that agency approval of their drug and its labeling prec...
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Probiotic bacteria are administered as live microorganisms to provide a health benefit to the host. Insight into the adaptation factors that promote the survival and persistence of probiotics in the gastrointestinal tract (GIT) is important to understand their performance. In this study, the role of the long galactose-rich exopolysaccharides (EPS) of the prototypical probiotic strain Lactobacil...
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PURPOSE An earlier randomized controlled study found that a universal, family-focused preventive intervention produced protective shield effects-reduced adolescent exposures to illicit substance opportunities-among adolescents in grade 12. This study examined a follow-up assessment of the sample during young adulthood. METHODS A randomized controlled trial evaluated the Iowa Strengthening Fam...
متن کاملTrigger factor forms a protective shield for nascent polypeptides at the ribosome.
In prokaryotes, the ribosome-associated Trigger Factor is the first chaperone newly synthesized polypeptides encounter when they emerge from the ribosomal exit tunnel. The effects that Trigger Factor exerts on nascent polypeptides, however, remain unclear. Here we analyzed the potential of the Trigger Factor to shield nascent polypeptides at the ribosome. A set of arrested nascent polypeptides ...
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The last instar larva and pupa of Eucoeliodes mirabilis (A. Villa & G. B. Villa, 1835) (Curculionidae: Ceutorhynchini) are described using drawings and SEM images and are compared and keyed with already described larvae of 58 other ceutorhynchinae taxa. The larval body has an effective combination of morphological adaptations that assist a unique biological defensive strategy. All larval stages...
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ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2018
ISSN: 1465-7392,1476-4679
DOI: 10.1038/s41556-018-0152-x