AScutellaria baicalensis radixwater extract inhibits morphine-induced conditioned place preference
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چکیده
منابع مشابه
[Electroacupuncture suppresses morphine--induced conditioned place preference (CPP) in rats].
OBJECTIVE To examine the effects produced by electroacupuncture (EA) of different frequencies on the expression of morphine conditioned place preference (CPP) in rats. METHODS SD rats were given 4 days consecutive trials in a computerized three-chamber "unbiased" CPP apparatus. Twenty-four hours later, the time spent on drug-pairing compartment of the rat was examined. Rats trained with CPP p...
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UNLABELLED Serotonine reuptake inhibitors are an important pharmacological arsenal for treating major depression, a severe disease with poorly understood pathogenic mechanisms. Also, little is known about the action of antidepressants on reward system, the function of which is severely affected in this disorder. AIM To assess the influence of sertraline on brain reward system by conditioned p...
متن کاملGinger (Zingiber Officinale Roscoe) Prevents Morphine-Induced Addictive Behaviors in Conditioned Place Preference Test in Rats
Background: Consumption of chronic morphine induces neuro-inflammation and addictive seeking behavior. Ginger (Zingiber Officinale Roscoe), a well-known spice plant, has been used traditionally in the treatment of a wide variety of ailments. It has been shown that ginger has anti-inflammatory, anti-oxidative and antinociceptive properties. However, its influences on morphine-induced addictive b...
متن کاملEffects of berberine on acquisition and reinstatement of morphine-induced conditioned place preference in mice
Objective: It has been shown that berberine, a major component of Berberis vulgaris extract, modulates the activity of several neurotransmitter systems including dopamine (Da) and N-methyl-D-aspartate (NMDA) contributing to rewarding and reinforcing effects of morphine. Drug craving and relapsing even after a long time of abstinence therapy are the most important problems of addiction. In the p...
متن کاملPeripheral electric stimulation inhibits morphine-induced place preference in rats.
Conditioned place preference (CPP) is a commonly used model to detect rewarding effect of drugs. To observe the effect of peripheral electric stimulation (PES) on morphine-induced CPP, we trained the rats with morphine in a CPP paradigm. Twelve hours before the testing phase, rats were given PES via stainless-steel needles with frequencies of 2, 100, or 2/100 Hz, respectively. PES of 2 and 2/10...
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ژورنال
عنوان ژورنال: Pharmaceutical Biology
سال: 2014
ISSN: 1388-0209,1744-5116
DOI: 10.3109/13880209.2014.892514