Arts & Literature: The Grey Zone

The grey zone of truth.

Registration of new drugs and devices, and our guidelines for management of cardiovascular disease, are mostly based on the results of clinical trials. Trial results are reported in great detail, with primary and secondary endpoints, event rates in the relevant treatment groups, relative risks or odds ratios with confidence intervals, and the corresponding statistical analyses. However, the bus...

Literature and the arts in medical education.

Editor’s Note: In this column, teachers who are currently using literary and artistic materials as part of their curricula will briefly summarize specific works, delineate their purposes and goals in using these media, describe their audience and teaching strategies, discuss their methods of evaluation, and speculate about the impact of these teaching tools on learners (and teachers). Submissio...

Hodgkin’s lymphoma and Grey-zone lymphomas

Grey Zone Lymphomas: Lymphomas with Intermediate Features

The current classification of lymphoid neoplasms is based on clinical information, morphology, immunophenotype, and molecular genetic characteristics. Despite technical and scientific progress, some aggressive B-cell lymphomas with features overlapping between two different types of lymphomas remain difficult to classify. The updated 2008 World Health Organization (WHO) classification of Tumour...

The limits of perinatal viability: grappling with the "grey zone".

On balance, new guidelines for parents and practitioners are helpful and workable hich infants at the margins of viability should receive neonatal intensive care and how should such decisions be made? These challenging questions are posed in this issue of the Journal by Lui and colleagues (page 495). 1 Their answers, arrived at by means of a multidisciplinary conference, are presented as a cons...