Artificial antibodies
نویسندگان
چکیده
منابع مشابه
Towards artificial antibodies prepared by molecular imprinting.
The new technique of molecular imprinting has increasingly been adopted by research laboratories worldwide during the last few years. We have studied the use of such imprints against drugs as artificial antibody-binding mimics in competitive radioimmuno-style binding assays. The recognition sites "molded" in the polymers mimic the binding sites of natural antibodies in their interactions with t...
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The gene VII protein (pVII) and gene IX protein (pIX) are associated closely on the surface of filamentous bacteriophage that is opposite of the end harboring the widely exploited pIII protein. We developed a phagemid format wherein antibody heavy- and light-chain variable regions were fused to the amino termini of pVII and pIX, respectively. Significantly, the fusion proteins interacted to for...
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Two binary-encoded models describing some aspects of the evolution in an artificial immune system have been proposed and analyzed. The first model has focused on the evolution of a paratope's population, considering a fixed group of epitopes, to simulate a hypermutation mechanism and observe how the system would self-adjust to cover the epitopes. In the second model, the evolution involves a gr...
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ژورنال
عنوان ژورنال: Nature Photonics
سال: 2012
ISSN: 1749-4885,1749-4893
DOI: 10.1038/nphoton.2012.354