Article Watch: September 2013

Antibodies to watch in 2013

The transitions of antibody therapeutics to late-stage clinical development, regulatory review and the market are proceeding at a rapid pace in 2013. Since late 2012, two monoclonal antibody (mAb) therapeutics (itolizumab, trastuzumab emtansine) received their first approvals, first marketing applications for three mAbs (vedolizumab, ramucirumab, obinutuzumab) were submitted to regulatory agenc...

Package ‘ surveillance ’ September 9 , 2013

In the September 2013 issue

Package ‘ Zelig ’ September 21 , 2013

Description Zelig is an easy-to-use program that can estimate, and help interpret the results of, an enormous range of statistical models. It literally is ‘‘everyone’s statistical software’’ because Zelig’s simple unified framework incorporates everyone else’s (R) code. We also hope it will become ‘‘everyone’s statistical software’’ for applications and teaching, and so have designed Zelig so t...

Package ‘ AICcmodavg ’ September 12 , 2013

Description This package includes functions to create model selection tables based on Akaike’s information criterion (AIC) and the second-order AIC (AICc), as well as their quasi-likelihood counterparts (QAIC, QAICc). Tables are printed with delta AIC and Akaike weights. The package also features functions to conduct classic model averaging (multimodel inference) for a given parameter of intere...