Artery Wall Assessment Helps Predict Kidney Transplant Outcome
نویسندگان
چکیده
منابع مشابه
Artery Wall Assessment Helps Predict Kidney Transplant Outcome
BACKGROUND Kidney transplant recipients have high cardiovascular risk, and vascular inflammation may play an important role. We explored whether the inflammatory state in the vessel wall was related to carotid intima-media thickness (c-IMT) and patient survival following kidney transplantation. METHODS In this prospective observational cohort study we measured c-IMT and expression of proinfla...
متن کاملGazing into a crystal ball to predict kidney transplant outcome.
Kidney transplantation is the optimal therapy for end-stage kidney disease but requires lifelong immunosuppression. Despite improvements in immunosuppression regimens that have reduced rates of acute transplant rejection, long-term allograft survival remains suboptimal. More than 50% of transplanted kidneys from deceased donors fail within 10 years. In order to improve long-term outcomes, physi...
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Although renal transplant is the preferred modality for end-stage renal disease, it brings with it a number of challenges primarily associated with lack of individualized approach. The goals of the present project were: (1) to determine the most significant and clinically practical predictors of kidney transplant outcomes (patient survival, allograft survival, posttransplant complications) usin...
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IJKD 2013;7:352-5 www.ijkd.org 1Department of Renal Medicine and Transplantation, St George’s Hospital, Blackshaw Road, London, United Kingdom 2Department of Surgery, Louisiana State Unieversity Health Sciences CenterShreveport, Los Angeles, United States 3Institute for Clinical and Experimental Medicine and 2nd Medical Faculty, Charles University, Prague, Czech Republic 4Department of Radiolog...
متن کاملSystematic assessment of the influence of complement gene polymorphisms on kidney transplant outcome.
The importance of the innate immune system, including complement, in causing transplant injury and augmenting adaptive immune responses is increasingly recognized. Therefore variability in graft outcome may in part be due to genetic polymorphism in genes encoding proteins of the immune system. This study assessed the relationship between single nucleotide polymorphisms (SNPs) in complement gene...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0129083