Arsenical Pigmentation and Hyperkeratosis. Disseminated Sclerosis with Epilepsy

Tuberous Sclerosis with Disseminated Malignancy.

Tuberous sclerosis is characterized by typical skin and clinical manifestations with predilection to neoplasia. We describe the case of a 42-year old female who presented with a mass and pain in right lumbar region with constitutional symptoms and generalized body aches since last one year. She had adenoma sebaceum, subungual fibromas and hepatomegaly. CT chest, abdomen and MRI revealed mass in...

Prevalence of Disseminated Sclerosis

CHARCOT remarked in 1868: "Even today I do not believe that disseminated sclerosis is known in England," and this may have been true, although Moxon described a case in 1873 and others some years later. Williamson (1903) reported a proportion of patients with disseminated sclerosis equivalent to 27 cases for every 1,000 nervous diseases seen at the Manchester Royal Infirmary over a period of 10...

Veterinary Workers and Disseminated Sclerosis.

Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies

  Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies.   Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...

Eye Changes in Disseminated Sclerosis

What is probably the first written account of the clinical features of disseminated sclerosis is contained in the diary of Augustus D'Este, the illegitimate son of Prince Augustus Frederick, and grandson of George III. The first manifestations of the disease in his case, as m some 30% of all such patients, were referable to the eyes. In 1822, we read, he journeyed to visit a much-loved relative...