Aromatic Thioacetal-Bridged ROS-Responsive Nanoparticles as Novel Gene Delivery Vehicles

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ROS‐responsive drug delivery systems

Reactive oxygen species (ROS) play an important role in signal transduction and metabolism. Over-produced ROS in cells or tissues, however, often leads to oxidation stress that has implications in a series of diseases including cancer, aging, atherosclerosis and inflammation. Driven by the need for on-demand drug delivery and fuelled by recent development of ROS-responsive materials and nanomed...

متن کامل

Discrete thermally responsive hydrogel-coated gold nanoparticles for use as drug-delivery vehicles

This report describes the development of optically responsive gold nanoparticles ( 60 nm in diameter) coated with a thermally responsive biocompatible hydrogel overlayer (20–90 nm thick). The hydrogel consists of a mixture of N-isoproprylacrylamide and acrylic acid; this copolymer can be tailored to exhibit a lower critical solution temperature (LCST) slightly above physiological temperature. W...

متن کامل

Functionalized Mesoporous Silica Nanoparticles as a Novel Antioxidant Delivery System

Antioxidants have an important role in control and prevention of dangerous diseases like cancers, but instability and high solubility of the antioxidants are <span style="font-size: 11pt; color: #00000...

متن کامل

Mesenchymal Stem Cells as Gene Delivery Vehicles

Mesenchymal stem cells (MSCs) possess a battery of unique properties which make them ideally suited not only for cellular therapies/regenerative medicine, but also as vehicles for gene delivery in a wide array of clinical settings. These include: 1) widespread distribution throughout the body; 2) ease of isolation and ability to be extensively expanded in culture without loss of potential; 3) t...

متن کامل

Novel pDNA nanoparticles for pulmonary gene delivery

The development of new therapies by gene transfer to the lung epithelial cells is an attractive prospect because of the potential ease of access to a vast surface area of tissue and the prospects for administration of gene vectors by inhalation. A number of respiratory diseases could benefit from this approach, including cystic fibrosis (CF), and more common chronic conditions such as asthma an...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Molecules

سال: 2018

ISSN: 1420-3049

DOI: 10.3390/molecules23082061