Armadillo Repeat Containing 8α Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins

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Armadillo Repeat Containing 8α Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins

Recently, we reported that a complex with an essential role in the degradation of Fructose-1,6-bisphosphatase in yeast is well conserved in mammalian cells; we named this mammalian complex C-terminal to the Lissencephaly type-1-like homology (CTLH) complex. Although the function of the CTLH complex remains unclear, here we used yeast two-hybrid screening to isolate Hepatocyte growth factor-regu...

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After Hrs with HIV

To efficiently bud off from infected cells, HIV and other enveloped viruses hijack the host cellular machinery that is normally involved in vacuolar protein sorting and multivesicular body (MVB) biogenesis. The HIV Gag protein mimics hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs), a modular adaptor protein that links membrane cargo recognition to its degradation after delive...

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2 hrS . AN L ES Ll - - - - 2 & hrS . - - - - - - -

Two problems confront the spinal anaesthetist when he makes his injection :i. Which are the spinal nerve roots carrying the pain impulses from the operation area. This problem will not be further considered. It involves basic anatomical knowledge with which the anaesthetist must make himself familiar. 2. How is the local anaesthetic, deposited in the lumbar region, to be brought into contact wi...

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ACCF/AHA/HRS Practice Guideline

Andrew E. Epstein, MD, FACC, FAHA, FHRS, Chair; John P. DiMarco, MD, PhD, FACC, FHRS; Kenneth A. Ellenbogen, MD, FACC, FAHA, FHRS; N.A. Mark Estes III, MD, FACC, FAHA, FHRS; Roger A. Freedman, MD, FACC, FHRS; Leonard S. Gettes, MD, FACC, FAHA; A. Marc Gillinov, MD, FACC, FAHA; Gabriel Gregoratos, MD, FACC, FAHA; Stephen C. Hammill, MD, FACC, FHRS; David L. Hayes, MD, FACC, FAHA, FHRS; Mark A. H...

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Armadillo repeat proteins: beyond the animal kingdom.

Armadillo (Arm) repeat proteins contain tandem copies of a degenerate protein sequence motif that forms a conserved three-dimensional structure. Animal Arm repeat proteins function in various processes, including intracellular signalling and cytoskeletal regulation. A subset of these proteins are conserved across eukaryotic kingdoms, and non-metazoa such as Dictyostelium and Chlamydomonas posse...

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ژورنال

عنوان ژورنال: The Open Biochemistry Journal

سال: 2010

ISSN: 1874-091X

DOI: 10.2174/1874091x01004010001