Aripiprazole for acute mania in an elderly person

Aripiprazole alone or in combination for acute mania.

BACKGROUND Bipolar disorder is a mental disorder characterised by episodes of elevated or irritable mood (manic or hypomanic episodes) and episodes of low mood and loss of energy (depressive episodes). Drug treatment is the first-line treatment for acute mania with the initial aim of rapid control of agitation, aggression and dangerous behaviour. Aripiprazole, an atypical antipsychotic, is used...

Aripiprazole monotherapy in acute mania : 12 - week randomised

Bipolar disorder is a lifelong episodic illness requiring long-term treatment, yet there remains a need for well-tolerated and clinically effective maintenance of effect and continuation therapies. Aripiprazole has a novel pharmacological profile; partial agonism at dopamine D 2 and D 3 and serotonin 5-HT 1A receptors, and antagonism at 5-HT 2A receptors. 1–5 Aripiprazole has been shown to impr...

Non-Fatal Amlodipine and Insulin Overdose in an Elderly Person

[Advances in the treatment of mania: aripiprazole].

Aripiprazole is a dopamine partial agonist antipsychotic drug that has just been approved in Europe for its use in the treatment of acute mania and for the prevention of manic episodes in bipolar disorder. Its efficacy in mania is superior to that of placebo, both as monotherapy and as adjunctive therapy, and comparable to that of haloperidol and lithium. From the safety perspective it is remar...

comparison the effectiveness of aripiprazole and risperidone for the treatment of acute bipolar mania

background: second-generation antipsychotics, approved for the treatment of mania, are associated with adverse effects such as weight gain and metabolic disorders. aripiprazole, a recently introduced second-generation antipsychotic, are thought to account for its low propensity for weight gain, metabolic disturbances and sedation. the purpose of this study was to investigate the effect of rispe...