Are there subtle genome-wide epigenetic alterations in normal offspring conceived by assisted reproductive technologies?
نویسندگان
چکیده
منابع مشابه
Cardiovascular dysfunction in children conceived by assisted reproductive technologies.
Epidemiological studies demonstrate a relationship between pathological events during foetal development and future cardiovascular risk and the term 'foetal programming of cardiovascular disease' has been coined to describe this phenomenon. The use of assisted reproductive technologies (ARTs) is growing exponentially and 2-5% of children are now born by this procedure. Emerging evidence indicat...
متن کاملAlterations in the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology.
STUDY QUESTION How does the frequency of trinucleotide repeat dynamic mutations in offspring conceived through assisted reproductive technology (ART) compare with the frequency of these mutations in control offspring conceived from spontaneous pregnancies? SUMMARY ANSWER There is a slight increase in dynamic mutation instability in offspring conceived through ART compared with the naturally c...
متن کاملCongenital Malformations in Singleton Infants Conceived by Assisted Reproductive Technologies and Singleton Infants by Natural Conception in Tehran, Iran
Objective Multiple pregnancies occur more frequently in assisted reproductive technology (ART) compared to normal conception (NC). It is known that the risk of congenital malformations in a multiple pregnancy are higher than single pregnancy. The aim of this study is to compare congenital malformations in singleton infants conceived by ART to singleton infants conceived naturally. MaterialsAndM...
متن کاملDown Syndrome Screening in Pregnancies Conceived after Assisted Reproductive Technologies
Over the last three decades, prenatal screening for Down syndrome and other chromosomal abnormalities has become routine during antenatal care. Down syndrome screening has changed from the second to the first trimester of pregnancy because of the higher detection rate and earlier diagnosis. Second-trimester screening, based on the combination of maternal serum human chorionic gonadotropin (hCG)...
متن کاملA Comparison of Postpartum Depression in Mothers Conceived by Assisted Reproductive Technology and Those Naturally Conceived
Objective It is thought that mothers who conceive via assisted reproductive technology (ART) may be at greater risk of postpartum depression (PPD) because of the problems and psychological stresses associated with ART treatment. The aim of the present study is to determine the occurrence of PPD among mothers conceiving via ART in comparison with mothers naturally conceiving, using Edinburgh Pos...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2011
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2011.09.037