منابع مشابه
Are acquired variations inherited?
Are acquired characteristics inherited? We admit that individuals inherit a certain constitution, and that definite variations from this constitution are acquired during life-time, according to well-known laws. The question is: Are these definite acquired variations in any degree transmitted, or are the congenital variations in the constitution of the offspring independent of those which have b...
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Much of our view of mutation has been structured by the original viewpoints of Charles Darwin and Hugo de Vries. Darwin’s view has had particular importance because of the central role mutation plays in his theory of biological evolution. Mutation provides the variation (raw material) upon which natural selection acts. Implicit in this view is a very important assumption. In Darwin’s model, sel...
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Acquired aplastic anemia is a clinical syndrome in which there is a deficiency of red cells, neutrophils, monocytes, and platelets in the blood, and fatty replacement of the marrow with a near absence of hematopoietic precursor cells. Reticulocytopenia, neutropenia, monocytopenia, and thrombocytopenia, when severe, are life-threatening because of the risk of infection and bleeding, complicated ...
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VOLTAGE-GATED Na channels, transmembrane proteins that produce the ionic current responsible for the rapid upstroke of the cardiac action potential, are key elements required for rapid conduction through the myocardium and maintenance of the cardiac rhythm. As such, inherited mutations in SCN5A, the gene encoding the human cardiac Na channel (hH1; Fig. 1), are associated with a range of life-th...
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ژورنال
عنوان ژورنال: The American Naturalist
سال: 1891
ISSN: 0003-0147,1537-5323
DOI: 10.1086/275294