Aquaporin and Vascular Diseases

Aquaporin and Vascular Diseases

Aquaporins (AQP) are family of water channels found in several epithelial and endothelial cells, whose recent identification has provided insights into water transport in several tissues, including the central nervous system (CNS). Since brain edema continues to be the main cause of death from several CNS diseases, such as stroke, much of the interest in AQPs and their functional contribution t...

Aquaporin-4 and Cerebrovascular Diseases

Cerebrovascular diseases are conditions caused by problems with brain vasculature, which have a high morbidity and mortality. Aquaporin-4 (AQP4) is the most abundant water channel in the brain and crucial for the formation and resolution of brain edema. Considering brain edema is an important pathophysiological change after stoke, AQP4 is destined to have close relation with cerebrovascular dis...

Vascular Aging and Diseases: Molecular Mechanisms and Influences

Vascular aging plays an important role in the mortality of the elderly, but vascular aging can be dependent on other factors such as diseases. Various diseases such as Alzheimer, diabetes, thalassemia, and other diseases affect the mechanisms of vascular aging. It will harm the recovery process of these patients. There are methods for measuring vascular aging such as instrumental measurements a...

Profilin, and Vascular Diseases

Homocysteine and vascular diseases.

To the Editor: The article by Doshi et al in the January 1/8, 2002, issue of Circulation,1 in which the authors suggest that folic acid improves endothelial function by a mechanism largely independent of homocysteine (Hcy), prompted us to report our data on plasma Hcy levels before and after intravenous prostaglandin (PG) E1 -cyclodextrin in patients with systemic sclerosis. Ten patients with s...