Aptamer-conjugated magnetic nanoparticles as targeted magnetic resonance imaging contrast agent for breast cancer
نویسندگان
چکیده
منابع مشابه
aptamer-conjugated magnetic nanoparticles as targeted magnetic resonance imaging contrast agent for breast cancer
early detection of breast cancer is the most effective way to improve the survival rate in women. magnetic resonance imaging (mri) offers high spatial resolution and good anatomic details, and its lower sensitivity can be improved by using targeted molecular imaging. in this study, as1411 aptamer was conjugated to fe3o4@au nanoparticles for specific targeting of 4t1 cells that overexpress nucle...
متن کاملAptamer-conjugated Magnetic Nanoparticles as Targeted Magnetic Resonance Imaging Contrast Agent for Breast Cancer
Early detection of breast cancer is the most effective way to improve the survival rate in women. Magnetic resonance imaging (MRI) offers high spatial resolution and good anatomic details, and its lower sensitivity can be improved by using targeted molecular imaging. In this study, AS1411 aptamer was conjugated to Fe3O4@Au nanoparticles for specific targeting of mouse mammary carcinoma (4T1) ce...
متن کاملMultifunctional MIL-S─CUR@FC nanoparticles: a targeted theranostic agent for magnetic resonance imaging and tumor targeted delivery of curcumin
Introduction: Noninvasive magnetic resonance imaging (MRI) and targeted drug delivery systems, usually referred to as theranostic agents, are being developed to enable detection, site-specific treatment, and long-term monitoring. Materials and Methods: To elucidate the effects of coating on cellular uptake and biodistribution of n...
متن کاملGadolinium-Diethylenetriaminepenta-Acetic acid Conjugated with Monoclonal Antibody C595 as New Magnetic Resonance Imaging Contrast Agents for Breast Cancer (MCF-7) Detection
Background: The monoclonal antibody, C595, against breast cancer cell line was conjugated with cyclic anhydride gadolinium-diethylenetriaminepenta-acetic acid (Gd-cDTPAa) to produce Gd-DTPA-C595 and used as specific breast cancer cell line (MCF-7) contrast agents in magnetic resonance imaging (MRI). Methods: After incubation of breast cancer cell line (MCF-7), with different contrast agents (G...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Medical Signals & Sensors
سال: 2016
ISSN: 2228-7477
DOI: 10.4103/2228-7477.195093