April 20, 2004

Cover Vol.1, No.1, April 2004

New Books April 2004

Background: Two distinct classes of regulators have been implicated in regulating neuronal gene expression and mediating neuronal identity: transcription factors such as REST/NRSF (RE1 silencing transcription factor) and CREB (cAMP response element-binding protein), and microRNAs (miRNAs). How these two classes of regulators act together to mediate neuronal gene expression is unclear. Results: ...

The NEBLINE, April 2004

Extramural Update April 2004

Background: The respiratory pathogen Bordetella parapertussis is a valuable model in which to study the complex phenotype of host specificity because of its unique two-species host range. One subset of strains, including the sequenced representative, causes whooping cough in humans, while other strains infect only sheep. The disease process in sheep is not well understood, nor are the genetic a...

Corrections April 2004

No truer words have been spoken about a chemically injured patient—but more words could be added. Alas, mainstream doctors are not trained adequately to diagnose symptoms and adverse health events from pesticide poisoning, not even when the patient describes actual exposures to the doctor. Try to imagine what it is like for a patient suffering from perfume poisoning. I certainly hope that Grand...