Appropriate nomenclature: angiotensin II receptors

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Appropriate nomenclature: angiotensin II receptors.

Radford published an interesting clinical case report of rural patients taking angiotensin II type 1 (AT1) receptor antagonist – commonly also referred to as angiotensin receptor antagonists, AT1 receptor blockers, angiotensin receptor blockers or ARBs – who experienced a sudden loss of consciousness whilst exercising gently in the heat. The findings in this manuscript support, in a clinical se...

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The investigation of the interaction between angiotensin II and its receptors in human subjects has been hampered by the inaccessibility of human tissue containing angiotensin II receptors. In order to find a more accessible angiotensin II-binding tissue, we studied angiotensin II binding to platelets in normal human volunteers. Platelet preparations purified on Ficoll: Isopaque gradients were ...

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Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II-induced hypertension.

The angiotensin (Ang) type 1 receptor (AT1R) promotes functional and structural integrity of the arterial wall to contribute to vascular homeostasis, but this receptor also promotes hypertension. In our investigation of how Ang II signals are converted by the AT1R from physiological to pathological outputs, we found that the purinergic P2Y6 receptor (P2Y6R), an inflammation-inducible G protein ...

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ژورنال

عنوان ژورنال: Rural and Remote Health

سال: 2015

ISSN: 1445-6354

DOI: 10.22605/rrh3150