Appropriate conversion from valproate monotherapy to lamotrigine monotherapy in Japanese women with epilepsy
نویسندگان
چکیده
منابع مشابه
Visual function in epilepsy patients treated with initial valproate monotherapy
PURPOSE To investigate whether initial valproate (VPA) monotherapy for the treatment of epilepsy causes visual field defects and visual dysfunction. METHODS In a cross-sectional study, visual fields were examined with the kinetic Goldmann and automated Humphrey perimeters, contrast sensitivity function with the Pelli-Robson letter chart and colour vision with the Standard Pseudoisochromatic P...
متن کاملAction Tremor Associated with Lamotrigine Monotherapy
Lamotrigine (LTG) is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use. Based on the temporal relationship, it is conceivable that lamotrigine increases serotonin transmission or affects basal ganglia dopamine activity, th...
متن کاملRational conversion from antiepileptic polytherapy to monotherapy.
For patients with epilepsy, the goal of treatment is to achieve seizure freedom with minimal or no adverse events. Around 60%-70% of newly diagnosed patients will achieve this goal with single antiepileptic drug (AED) therapy, and there is universal agreement that prescription of a single agent constitutes best practice for such patients. For the 30%-40% of patients with poorly controlled epile...
متن کاملdisorder facial affect recognition with lamotrigine monotherapy in bipolar
Lamotrigine is a broad-spectrum anti-epileptic known to alleviate and prevent depression in bipolar disorder. 1–3 Its therapeutic mechanism remains unclear but at least in healthy controls it may increase brain activity in temporal and ventral prefrontal cortical regions. 4 These regions have also been implicated in the pathophysiology of bipolar disorder. 5–7 They are also part of a distribute...
متن کاملLevetiracetam monotherapy—Outcomes from an epilepsy clinic
INTRODUCTION Levetiracetam (LEV) is a broad spectrum antiepileptic drug (AED) with a unique mechanism of action. This retrospective audit explores outcomes in patients commenced on LEV monotherapy at the Epilepsy Unit at the Western Infirmary, Glasgow, Scotland from 1st January 2001 until 30th June 2009. METHODS LEV monotherapy was started in 228 patients (89 men, 139 women, aged 12-81 years ...
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ژورنال
عنوان ژورنال: Epilepsy & Seizure
سال: 2016
ISSN: 1882-5567
DOI: 10.3805/eands.8.21