Applications of CRISPR-Cas9 Technology to Treat CCR5 Tropic HIV-1

Human immunodeficiency virus type 1 (HIV-1) is most notable for its role in directly infecting and killing CD4 T cells the immune system, which can lead to acquisition of Acquired Immunodeficiency Syndrome (AIDS). Currently, there are no cures HIV-1, leaving 37 million people with HIV-1 infections definitive treatment. Researchers working towards developing long-term treatments using CRISPR-Cas9. These therapies include genetically engineering antiviral resistance into vulnerable cell types cutting out viral genomes from infected cells. This article will explain life cycle detail, give an overview CRISPR-Cas9 technology, then go detail about potential applications treatment CCR5 Tropic HIV-1.