Apomorphine-induced blinking and yawning in healthy volunteers.
نویسندگان
چکیده
منابع مشابه
Apomorphine-induced blinking and yawning in healthy volunteers.
Yawning and spontaneous blink rate (SBR) are two physiological reflexes which have been incompletely examined but one neurobiological step of these two behaviours seems, at least in part, dopamine-dependent. The reference dopaminergic agonist, apomorphine hydrochloride (0.5, 1, and 2 micrograms kg-1 s.c.), was compared with a placebo in a double-blind latin-square design, and was shown to induc...
متن کاملTurmeric active substance, curcumin, enhanced apomorphine-induced yawning in rats
Objective: Curcumin is a major constituent of turmeric and influences many functions of the brain. In the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats. Materials and Methods: Curcumin administered orallyfor 10 consecutive days. Yawning was induced by subcutaneous (s.c.) injection of apomorphine (a dopamine receptor agonist) and the number of ya...
متن کاملTurmeric active substance, curcumin, enhanced apomorphine-induced yawning in rats
OBJECTIVE Curcumin is a major constituent of turmeric and influences many functions of the brain. In the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats. MATERIALS AND METHODS Curcumin administered orally for 10 consecutive days. Yawning was induced by subcutaneous (s.c.) injection of apomorphine (a dopamine receptor agonist) and the number of y...
متن کاملturmeric active substance, curcumin, enhanced apomorphine-induced yawning in rats
objective: curcumin is a major constituent of turmeric and influences many functions of the brain. in the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats. materials and methods: curcumin administered orallyfor 10 consecutive days. yawning was induced by subcutaneous (s.c.) injection of apomorphine (a dopamine receptor agonist) and the number of ya...
متن کاملApomorphine effects on episodic memory in young healthy volunteers.
RATIONALE Dopamine (DA) modulates working memory. However, the relation between DA systems and episodic (declarative) memory is less established. Frontal lobe DA function may be involved. We were interested in assessing whether apomorphine (Apo), a drug used extensively in clinical research as a probe of DA function, has an effect on episodic memory test performance in healthy volunteers. OBJ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1990
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1990.tb03848.x