Apolipoprotein A1 rs5070 A/G polymorphism with stroke subtypes in Taiwan

Apolipoprotein A1 rs5070 A/G polymorphism with stroke subtypes in Taiwan.

BACKGROUND Apolipoprotein A1 (ApoA1) is a structural protein of high-density lipoprotein cholesterol; ApoA1 is involved in lipid and cholesterol metabolism. This study evaluated the association of ApoA1 polymorphism (rs5070) with different stroke subtypes in Taiwanese individuals. METHODS A total of 2139 cases, including 614 controls and 708 large artery atherosclerosis (LAA), 377 small-vesse...

a1-Antichymotrypsin Gene Polymorphism in Patients With Stroke

Background and Purpose—A role for proteolytic enzymes has been suggested in the pathogenesis of stroke. In a search for new genetic factors, we investigated the gene polymorphism of the serine protease inhibitor a1-antichymotrypsin (ACT) in patients with stroke. Methods—Two hundred twenty patients with acute ischemic stroke (n5182) and primary intracerebral hemorrhage (n538) and 70 control subj...

Evaluation of Apolipoprotein A5 Polymorphism in Coronary- Heart Disease Patients

Background and Objectives: Apolipoprotein A5 (APOA5) gene is important in determining plasma triglyceride levels, a major cardiovascular disease risk factor. Mutation in this gene affected plasma triglyceride level. We looked for possible associations of the APOA5 gene polymorphism S19W with coronary heart disease (CHD) in a sample of Iranian population. Materials and Methods: A total of 7...

Association of Apolipoprotein E Polymorphism with Susceptibility to Multiple Sclerosis

The association between small dense low density lipoprotein,apolipoprotein B, apolipoprotein B/apolipoprotein A1 ratio and coronary artery stenosis

  Abstract   Background: Recently, small dense low density lipoprotein (sdLDL) has been   highlighted as a new risk factor for the coronary artery disease (CAD).Small dense   LDLs are believed to be atherogenic since these particles are taken up more easily by   arterial wall. They are readily oxidized and have reduced affinity for low density   lipoprotein (LDL) receptor and increased affinity...