Apical Transport and Folding of Prostate-specific Membrane Antigen Occurs Independent of Glycan Processing
نویسندگان
چکیده
منابع مشابه
Apical transport and folding of prostate-specific membrane antigen occurs independent of glycan processing.
Prostate-specific membrane antigen (PSMA) is an integral cell-surface membrane glycoprotein that is overexpressed in prostate carcinomas rendering it an appropriate target for antibody-based therapeutic strategies. The biosynthesis of PSMA in transfected COS-1 cells reveals a slow conversion of mannose-rich to complex glycosylated PSMA compatible with slow transport kinetics from the endoplasmi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2006
ISSN: 0021-9258
DOI: 10.1074/jbc.m509460200